Creamy Cajun Chicken Spaghetti with Garlic Mozzarella Sauce – Easy & Flavor-Packed Dinner

Introduction

A Comfort Food Classic with a Cajun Twist

If you’re a fan of creamy pasta and bold spices, this Creamy Cajun Chicken Spaghetti is going to rock your dinner table. It’s rich, cheesy, and just the right amount of spicy. The best part? It comes together in just 30 minutes, making it the ultimate weeknight hero.

Why This Recipe Works

This recipe delivers layers of flavor in a single skillet. The Cajun-seasoned chicken gets golden and juicy, while the garlic mozzarella cream sauce wraps every noodle in indulgent, savory goodness. Think of it as your favorite Alfredo—just with way more attitude.

Key Ingredients and Their Roles

Spaghetti – The Base of it All

Spaghetti is perfect for soaking up the thick, cheesy sauce. You can also use linguine or fettuccine if that’s what you have on hand.

Chicken – Lean Protein with Bold Flavor

Thinly sliced chicken breast gets tossed in Cajun seasoning for a smoky, slightly spicy bite that balances the creaminess of the sauce.

Cajun Seasoning – The Soul of the Dish

This blend of paprika, garlic powder, cayenne, oregano, and thyme brings the heat and flavor that makes this dish sing.

Heavy Cream & Chicken Broth – The Silky Foundation

These two are the base of your sauce. Heavy cream brings richness while broth adds depth and keeps the sauce from being overly heavy.

Garlic & Butter – Flavor Power Duo

Butter gives the sauce its silky texture, while fresh garlic adds that irresistible aroma and flavor that takes it to the next level.

Mozzarella & Parmesan – Creamy Meets Tangy

Mozzarella melts beautifully into a stretchy, gooey sauce, while Parmesan adds a salty bite and depth of flavor.

Step-by-Step Cooking Instructions

Step 1 – Boil the Spaghetti Just Right

Bring a large pot of salted water to a boil. Add spaghetti and cook according to package instructions until al dente. Drain and set aside.

Step 2 – Season and Sear the Chicken

Season the chicken strips generously with Cajun seasoning. In a large skillet, heat olive oil over medium-high heat. Sauté the chicken for 6–8 minutes, until golden brown and cooked through. Remove and keep warm.

Step 3 – Build the Creamy Garlic Mozzarella Sauce

In the same skillet, melt the butter over medium heat. Add minced garlic and sauté for about 30 seconds, just until fragrant—don’t let it burn. Pour in the heavy cream and chicken broth, stirring well. Let it simmer for 2–3 minutes.

Step 4 – Combine Pasta, Chicken, and Sauce

Add in mozzarella and Parmesan cheese. Stir continuously until melted into a luscious sauce. Return the chicken and cooked spaghetti to the skillet. Toss everything until coated and heated through. Season with salt and pepper to taste.

Top with fresh parsley and serve hot!

Tips for Success

Use Fresh Garlic, Not Pre-Made Mince

Fresh garlic brings a sharper, more vibrant flavor that really stands out in a creamy sauce.

Don’t Overcook the Chicken

Overcooked chicken turns rubbery. Cook just until golden brown and done—then pull it off the heat.

Simmer, Don’t Boil the Cream Sauce

Keep the sauce at a gentle simmer. Boiling can cause it to separate or become grainy.

Add More Heat (If You Dare)

Want to kick it up a notch? Toss in a pinch of cayenne or a few dashes of hot sauce.

Recipe Variations to Try

Swap the Protein

Don’t love chicken? Try shrimp, sliced sausage, or even tofu for a meatless option.

Add Veggies for Color and Nutrition

Toss in spinach, sun-dried tomatoes, or bell peppers for a boost of nutrients and a pop of color.

Make It Low-Carb

Sub spaghetti with zucchini noodles or spaghetti squash to cut down on carbs without missing out on flavor.

What to Serve with Cajun Chicken Spaghetti

Garlic Bread

The perfect side to soak up any leftover sauce. Plus, more garlic = more deliciousness.

Simple Garden Salad

Balance out the richness with something crisp and fresh.

Grilled Veggie Sides

Charred zucchini, bell peppers, or asparagus are great complements.

Storing and Reheating Leftovers

Let leftovers cool completely, then store in an airtight container in the fridge for up to 3 days.

To reheat: Add a splash of milk or broth to bring the sauce back to life, then microwave in 30-second bursts, stirring in between.

Nutritional Information (Approx.)

• Calories: 640 kcal

• Servings: 4

• Protein: 39g

• Fat: 32g

• Carbohydrates: 45g

• Fiber: 3g

• Sugar: 2g

• Sodium: 700mg

Final Thoughts

This Creamy Cajun Chicken Spaghetti with Garlic Mozzarella Sauce is the kind of comfort food that satisfies every craving. It’s rich and spicy, creamy yet bright, and easy enough to whip up after a long day. Whether you’re cooking for guests or just treating yourself, this dish hits all the right notes. Go ahead—grab that fork and twirl up some bold Southern comfort.

FAQs

Q1: Can I use milk instead of heavy cream?
A: You can, but the sauce will be thinner. Try using half-and-half or adding a bit of cream cheese for thickness.

Q2: How spicy is Cajun seasoning?
A: It varies by brand, but it usually has a mild-to-medium heat. Start with less if you’re sensitive to spice.

Q3: Can I make this dish ahead of time?
A: Yes! Prep and store the pasta and sauce separately, then combine and reheat when ready to serve.

Q4: Is it freezer-friendly?
A: Not really—cream-based sauces tend to separate when frozen and thawed. It’s best eaten fresh or from the fridge.

Q5: What’s a good Cajun seasoning brand?
A: Tony Chachere’s or Slap Ya Mama are popular picks with a good balance of flavor and heat.

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